117569-61-6

Basic information

• Product Name: 2-(3-Ethynylphenyl)-1,3-dioxolane
• Synonyms: 2-(3-Ethynylphenyl)-1,3-dioxolane
• CAS NO: 117569-61-6
• Molecular Weight: 174.199
• Mol File: 117569-61-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3-Ethynylphenyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Ethynylphenyl)-1,3-dioxolane(117569-61-6)
• EPA Substance Registry System: 2-(3-Ethynylphenyl)-1,3-dioxolane(117569-61-6)

Safety Data

• Hazardous Substances Data: 117569-61-6(Hazardous Substances Data)

Upstream product

• 17789-14-9 3-(1,3-dioxolan-2-yl)-phenylbromide 

Downstream Products

• 77123-56-9 3-ethynylbenzaldehyde 

Relevant articles and documents

AMINO-5-[4-(DIFLUOROMETHOXY)-PHENYL]-5-PHENYLIMIDAZOLONE COMPOUNDS FOR THE INHIBITION OF BETA-SECRETASE

The present invention provides a 2-amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

Process for the preparation of ethynylbenzaldehydes

A multi-step process for the preparation of ethynylbenzaldehydes from bromo- or iodobenzaldehydes is disclosed. The arylhalogen is replaced with a protected ethynyl compound which is subsequently cleaved by base to form the arylacetylene. The aldehydic functionality is preserved by formation of a corresponding Schiff's base or acetal, and its subsequent regeneration by treatment with aqueous acid.