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Usage

Uses

Used in Pharmaceutical Industry:
4-fluoro-3-Morpholinoaniline is used as a building block for the synthesis of various pharmaceuticals due to its potential biological activity and its role in creating compounds with therapeutic properties.
Used in Pesticide Industry:
In the pesticide industry, 4-fluoro-3-Morpholinoaniline is utilized as a component in the development of new pesticides, leveraging its chemical structure to enhance the effectiveness of these products.
Used in Medicinal Chemistry Research:
4-fluoro-3-Morpholinoaniline is employed as a subject of study in medicinal chemistry research for its potential as an antitumor agent, with ongoing investigations into its specific biological activities and mechanisms of action.
Safety Note:
It is crucial to handle 4-fluoro-3-Morpholinoaniline with care due to its potential hazards if ingested, inhaled, or if it comes into contact with the skin or eyes. Adequate safety measures should be implemented in laboratory and industrial environments to mitigate risks associated with 4-fluoro-3-Morpholinoaniline.

Upstream product

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• 110-91-8 morpholine 
• 3863-11-4 3,4-difluoroaniline 

Relevant academic research and scientific papers

Ru(II)-Catalyzed Amination of Aryl Fluorides via η6-Coordination

We developed a Ru/hemilabile-ligand-catalyzed nucleophilic aromatic substitution (SNAr) of aryl fluorides as the limiting reagents. Significant ligand enhancement was demonstrated by the engagement of both electron-rich and neutral arenes in the SNAr amination without using excess arenes. Preliminary mechanistic studies revealed that the nucleophilic substitution proceeds on a η6-complex of the Ru catalyst and the substrate, and the hemilabile ligand facilitates dissociation of products from the metal center.

Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins

The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.

CARBAZOLE AND CARBOLINE COMPOUNDS FOR USE IN THE DIAGNOSIS, TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH AMYLOID OR AMYOLID-LIKE PROTEINS

The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.