1176238-50-8

Basic information

• Product Name: 2,6-[(di-tert-butoxycarbonyl)diimido]-3-benzyl-5-tert-butoxycarbonyl-1,3,5,7,16-pentaazacyclotetracosan-4-one
• Synonyms: 2,6-[(di-tert-butoxycarbonyl)diimido]-3-benzyl-5-tert-butoxycarbonyl-1,3,5,7,16-pentaazacyclotetracosan-4-one
• CAS NO: 1176238-50-8
• Molecular Weight: 772.042
• Mol File: 1176238-50-8.mol

Chemical Properties

• CAS DataBase Reference: 2,6-[(di-tert-butoxycarbonyl)diimido]-3-benzyl-5-tert-butoxycarbonyl-1,3,5,7,16-pentaazacyclotetracosan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-[(di-tert-butoxycarbonyl)diimido]-3-benzyl-5-tert-butoxycarbonyl-1,3,5,7,16-pentaazacyclotetracosan-4-one(1176238-50-8)
• EPA Substance Registry System: 2,6-[(di-tert-butoxycarbonyl)diimido]-3-benzyl-5-tert-butoxycarbonyl-1,3,5,7,16-pentaazacyclotetracosan-4-one(1176238-50-8)

Safety Data

• Hazardous Substances Data: 1176238-50-8(Hazardous Substances Data)

Upstream product

• 1000005-28-6 tert‐butyl N‐[({8‐[(8‐aminooctyl)amino]octyl}amino)({[(tert‐butoxy)carbonyl]amino})methylidene]carbamate 
• 220652-02-8 N,N?-bis(tert-butoxycarbonyl)-N-benzyl-S-methylisothiourea 

Relevant articles and documents

Synthesis of new linear guanidines and macrocyclic amidinourea derivatives endowed with high antifungal activity against Candida spp. and Aspergillus spp.

New linear and cyclic guanidines were synthesized and tested in vitro for their antifungal activity toward clinically relevant strains of Candida species, in comparison to fluconazole. Macrocyclic compounds showed a minimum inhibitory concentration in the micromolar range and a biological activity profile in some cases better than that of fluconazole. One macrocyclic derivative was also tested against Aspergillus species and showed high antifungal activity comparable to that of amphotericin B and itraconazole.