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117625-46-4

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117625-46-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 117625-46-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,6,2 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 117625-46:
(8*1)+(7*1)+(6*7)+(5*6)+(4*2)+(3*5)+(2*4)+(1*6)=124
124 % 10 = 4
So 117625-46-4 is a valid CAS Registry Number.
InChI:InChI=1/C23H31N3O5/c24-26-25-17-10-7-16(8-11-17)9-12-18(27)13-14-20-19(21(28)15-22(20)29)5-3-1-2-4-6-23(30)31/h1,3,7-8,10-11,13-14,18-22,27-29H,2,4-6,9,12,15H2,(H,30,31)/b3-1-,14-13+/t18?,19-,20-,21+,22-/m1/s1

117625-46-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (Z)-7-[(1R,2R,3R,5S)-2-[(E)-5-(4-azidophenyl)-3-hydroxypent-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid

1.2 Other means of identification

Product number -
Other names Az-18,19,20-TN-PGE2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:117625-46-4 SDS

117625-46-4Upstream product

117625-46-4Downstream Products

117625-46-4Relevant articles and documents

Prostaglandin Photoaffinity Probes: Synthesis and Biological Activity of Azide-Substituted 16-Phenoxy- and 17-Phenyl-PGF2α Prostaglandins

Kawada, Kenji,Dolence, E. Kurt,Morita, Hiroyuki,Kometani, Tadashi,Watt, David S.,et al.

, p. 256 - 264 (2007/10/02)

The development of a prostaglandin PGF2α photoaffinity probe led to the synthesis and biological evaluation of azide-substituted 17-phenyl-18,19,20-trinorprostaglandin F2α and 16-phenoxy-17,18,19,20-tetranorprostaglandin F2α derivatives.Two approaches for the preparation of iodinated versions of these prostaglandins were evaluated: (1) iodination of a phenyl azide bearing an activating hydroxyl group and (2) iodination of an aniline precursor to the phenyl azide group and subsequent conversion of the aniline to the phenyl azide.In the first approach, 17-(4-azido-2-hydroxyphenyl)-18,19,20-trinorprostaglandin F2α, 16-(5-azido-3-hydroxyphenoxy)-17,18,19,20-tetranorprostaglandin F2α, and 16-(4-azido-2-hydroxyphenoxy)-17,18,19,20-tetranorprostaglandin F2α were prepared by using the Corey synthesis, but were biologically inactive presumably as a result of the hydrophilic phenolic hydroxyl group.In the second approach, the iodination of a 17-(4-aminophenyl)-18,19,20-trinorprostaglandin F2α derivative delivered 17-(4-azido-3-iodophenyl)-18,19,20-trinorprostaglandin F2α, which exhibited competitive binding with natural PGF2α to ovine luteal cells and to plasma membranes of bovine corpora lutea. -17-(4-Azido-3-iodophenyl)-18,19,20-trinorprostaglandin F2α was utilized in a preliminary photoaffinity cross-linking experiment.

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