117635-47-9Relevant academic research and scientific papers
Efficient and environmentally friendly Glaser coupling of terminal alkynes catalyzed by multinuclear copper complexes under base-free conditions
Zhang, Ling-Juan,Wang, Yan-Hong,Liu, Jie,Xu, Mei-Chen,Zhang, Xian-Ming
, p. 28653 - 28657 (2016)
An efficient catalytic system with dinuclear complex [Cu2(ophen)2] 1 and tetranuclear complex [Cu4(ophen)4(tp)] 2 as catalysts has been developed for the Glaser coupling reaction, which adopts environmentally fr
A convenient route to 1,3-diynes using ligand-free Cadiot–Chodkiewicz coupling reaction at room temperature under aerobic conditions
Asha, Sujatha,Anjana, Sasidharan,Thomas, Anns Maria,Thomas, Minu Elizabeth,Rohit,Krishnan, K. Keerthi,Ujwaldev, Sankuviruthiyil M,Anilkumar, Gopinathan
supporting information, p. 256 - 265 (2019/01/24)
In this study, we report a copper-catalyzed ligand-free Cadiot–Chodkiewicz coupling reaction. No additives or ligands are required for this Cu-catalyzed C(sp)–C(sp) coupling reaction of terminal alkynes with alkynyl halides. The low cost of copper catalyst, excellent yield of the products, suppression of side-products and mild reaction conditions are the major advantages of this protocol.
Transition metal-free coupling of terminal alkynes and hypervalent iodine-based alkyne-transfer reagents to access unsymmetrical 1,3-diynes
Sch?rgenhumer,Waser
, p. 7561 - 7563 (2018/11/02)
A variety of unsymmetrical 1,3-diynes can easily be accessed in good yields under catalyst- and transition metal-free conditions by reacting terminal alkynes with hypervalent iodine-based electrophilic alkyne-transfer reagents.
Highly efficient synthesis of unsymmetrical 1,3-diynes from organoalane reagents and alkynyl bromides mediated by a nickel catalyst
Mo, Song,Shao, Xue-Bei,Zhang, Gang,Li, Qing-Han
, p. 27243 - 27247 (2017/07/11)
Highly efficient and simple cross-coupling reactions of alkynylbromides with organoalane reagents for the synthesis of unsymmetrical 1,3-diynes derivatives using Ni(OAc)2 (2-5 mol%)/(o-furyl)3P (4-10 mol%) as a catalyst are reported. Excellent yields (up to 94%) were obtained for a wide range of substrates at rt or 60 °C for 2-3 h in Et2O or toluene.
Gold-Catalyzed Cadiot–Chodkiewicz-type Cross-Coupling of Terminal Alkynes with Alkynyl Hypervalent Iodine Reagents: Highly Selective Synthesis of Unsymmetrical 1,3-Diynes
Li, Xiangdong,Xie, Xin,Sun, Ning,Liu, Yuanhong
supporting information, p. 6994 - 6998 (2017/06/08)
A new and efficient method for the synthesis of unsymmetrical 1,3-butadiynes by gold-catalyzed C(sp)–C(sp) cross-coupling of terminal alkynes with alkynyl hypervalent iodine(III) reagents has been developed. The reaction features high selectivity and efficiency, mild reaction conditions, wide substrate scope, and functional-group compatibility, and is a highly attractive complement to existing methods. Mechanistic studies reveal that formation of a phenanthrolinyl-ligated gold(I) complex is crucial for the efficiency and selectivity of the target transformation.
Cu (I) immobilized on functionalized SBA-15: A recyclable catalyst for the synthesis of 1,3-diynes using terminal alkynes without base
Ma, Zongyan,Wang, Xiaoyu,Wei, Shuoyun,Yang, Honglei,Zhang, Fengwei,Wang, Peng,Xie, Miao,Ma, Jiantai
, p. 24 - 29 (2013/07/26)
A new functionalized SBA-15 catalyst immobilized CuI was successfully prepared, and the catalytic activity was tested in the oxidative homocoupling of terminal alkynes at the absence of base, and good to excellent yields was obtained to get 1,3-diynes without any side product formation in the solution of DMSO. Moreover, the system also allowed the synthesis of unsymmetric 1,3-diynes by cross-coupling of two different terminal alkynes. Finally, the catalyst could be reused for several times without a significant loss of activity.
An efficient copper-catalyzed homocoupling of terminal alkynes to give symmetrical 1,4-disubstituted 1,3-diynes
Zhang, Songlin,Liu, Xiaoyan,Wang, Tongqiang
supporting information; experimental part, p. 1463 - 1466 (2011/08/07)
A facile and efficient pathway for the copper iodide and ligand N,N,N',N'-tetramethylethane-1,2-diamine promoted homocoupling reaction of terminal alkynes under ambient temperature and air as an oxidant was reported. The alkynes, including aromatic alkynes and aliphatic alkynes, could afford the symmetrical 1,4-disubstituted 1,3-diynes in good to excellent yields. Copyright
Novel Synyhesis of Unsymmetrical Diarylbutadiynes
Nye, Susan Adams,Potts, Kevin T.
, p. 375 - 377 (2007/10/02)
Terminal arylbutadiynes, derived from 6-aryl-3,5-hexadin-2-ols, undergo a ready palladium-catalyzed coupling with activated aryl halides in the presence of a phase transfer catalyst to unsymmetrical diarylbutadiynes, not easily available by other coupling
