117635-48-0Relevant academic research and scientific papers
A convenient route to 1,3-diynes using ligand-free Cadiot–Chodkiewicz coupling reaction at room temperature under aerobic conditions
Asha, Sujatha,Anjana, Sasidharan,Thomas, Anns Maria,Thomas, Minu Elizabeth,Rohit,Krishnan, K. Keerthi,Ujwaldev, Sankuviruthiyil M,Anilkumar, Gopinathan
, p. 256 - 265 (2019/01/24)
In this study, we report a copper-catalyzed ligand-free Cadiot–Chodkiewicz coupling reaction. No additives or ligands are required for this Cu-catalyzed C(sp)–C(sp) coupling reaction of terminal alkynes with alkynyl halides. The low cost of copper catalyst, excellent yield of the products, suppression of side-products and mild reaction conditions are the major advantages of this protocol.
Highly efficient synthesis of unsymmetrical 1,3-diynes from organoalane reagents and alkynyl bromides mediated by a nickel catalyst
Mo, Song,Shao, Xue-Bei,Zhang, Gang,Li, Qing-Han
, p. 27243 - 27247 (2017/07/11)
Highly efficient and simple cross-coupling reactions of alkynylbromides with organoalane reagents for the synthesis of unsymmetrical 1,3-diynes derivatives using Ni(OAc)2 (2-5 mol%)/(o-furyl)3P (4-10 mol%) as a catalyst are reported. Excellent yields (up to 94%) were obtained for a wide range of substrates at rt or 60 °C for 2-3 h in Et2O or toluene.
Rapid access to unsymmetrical 1,3-diynes and 2,5-disubstituted thiophenes under ligand and Pd/Ni-free Cu-catalysis
Rao, Maddali L. N.,Islam, Sk Shamim,Dasgupta, Priyabrata
, p. 78090 - 78098 (2015/09/28)
A Pd/Ni-free copper-catalysed tandem synthesis was realized for rapid access to unsymmetrical 1,3-diynes from 1,1-dibromoalkenes and terminal alkynes. This method was extended to the straightforward synthesis of unsymmetrical 2,5-disubstituted thiophenes
Novel Synyhesis of Unsymmetrical Diarylbutadiynes
Nye, Susan Adams,Potts, Kevin T.
, p. 375 - 377 (2007/10/02)
Terminal arylbutadiynes, derived from 6-aryl-3,5-hexadin-2-ols, undergo a ready palladium-catalyzed coupling with activated aryl halides in the presence of a phase transfer catalyst to unsymmetrical diarylbutadiynes, not easily available by other coupling
