117664-56-9

Basic information

• Product Name: 3-(4-fluorophenyl)-2-phenyl-1,3-thiazolidin-4-one
• Synonyms: 3-(4-fluorophenyl)-2-phenyl-1,3-thiazolidin-4-one
• CAS NO: 117664-56-9
• Molecular Formula: C₁₅H₁₂FNOS
• Molecular Weight: 273.3252832
• Mol File: 117664-56-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-fluorophenyl)-2-phenyl-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)-2-phenyl-1,3-thiazolidin-4-one(117664-56-9)
• EPA Substance Registry System: 3-(4-fluorophenyl)-2-phenyl-1,3-thiazolidin-4-one(117664-56-9)

Safety Data

• Hazardous Substances Data: 117664-56-9(Hazardous Substances Data)

Upstream product

• 331-98-6 N-benzylidene-4-fluoroaniline 
• 68-11-1 mercaptoacetic acid 

Downstream Products

• 117664-63-8 Phenyl-dithiocarbamic acid 3-(4-fluoro-phenyl)-4-oxo-2-phenyl-thiazolidin-5-yl ester 
• 117664-67-2 [6-(4-Fluoro-phenyl)-5-phenyl-5,6-dihydro-[1,3]dithiolo[4,5-d]thiazol-(2E)-ylidene]-phenyl-amine 
• 117664-71-8 [6-(4-Fluoro-phenyl)-5-phenyl-5,6-dihydro-1-oxa-3,4-dithia-6-aza-pentalen-(2E)-ylidene]-phenyl-amine 
• 117664-74-1 4-(4-Fluoro-phenyl)-3,5-diphenyl-4,5-dihydro-3H-thiazolo[4,5-d]thiazole-2-thione 
• 117664-60-5 5-Bromo-3-(4-fluoro-phenyl)-2-phenyl-thiazolidin-4-one 

Relevant articles and documents

A catalysis study of mesoporous MCM-41 supported Schiff base and CuSO4·5H2O in a highly regioselective synthesis of 4-thiazolidinone derivatives from cyclocondensation of mercaptoacetic acid

Mesoporous MCM-41 supported Schiff base and CuSO4·5H2O shows high catalytic activity in the cyclocondensation of mercaptoacetic acid with imines (or aldehydes and amines) to afford pharmaceutically important thiazolidinone derivatives. The catalytic reactions involving two-components or three-components afforded the desired product in high yields (up to 98% and 99%). Moreover, the catalyst works well with respect to recyclability, giving the product in 85% and 83% yields after recycling six times.