1176702-57-0 Usage
Organic compound
Carboxylic acid This compound is an organic molecule that belongs to the class of carboxylic acids, which are characterized by the presence of a carboxyl functional group (-COOH).
Non-steroidal anti-inflammatory drug (NSAID)
It is commonly used as an NSAID, which is a type of medication that helps reduce inflammation, pain, and fever.
Analgesic and anti-inflammatory properties
2-(2-chloro-6-fluorophenyl)-2-methylpropanoic acid is known for its ability to relieve pain (analgesic) and reduce inflammation (anti-inflammatory) in the body.
Inhibition of prostaglandin production
The compound works by inhibiting the production of prostaglandins, which are hormone-like substances responsible for causing pain and inflammation.
Relief of symptoms for various conditions
It is often used to alleviate symptoms of conditions such as arthritis, menstrual cramps, and other types of pain.
Potential side effects
Although effective in relieving pain and inflammation, 2-(2-chloro-6-fluorophenyl)-2-methylpropanoic acid may also have potential side effects that should be considered.
Caution and medical guidance
It is important to use this compound with caution and under the guidance of a medical professional to ensure safe and effective use.
Check Digit Verification of cas no
The CAS Registry Mumber 1176702-57-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,6,7,0 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1176702-57:
(9*1)+(8*1)+(7*7)+(6*6)+(5*7)+(4*0)+(3*2)+(2*5)+(1*7)=160
160 % 10 = 0
So 1176702-57-0 is a valid CAS Registry Number.
1176702-57-0Relevant articles and documents
Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors
Teng, Xin,Keys, Heather,Jeevanandam, Arumugasamy,Porco Jr., John A.,Degterev, Alexei,Yuan, Junying,Cuny, Gregory D.
, p. 6836 - 6840 (2008/03/14)
Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling non-regulated necrosis. This form of cell death can be induced in an array of cell types in apoptotic deficient conditions with death receptor family ligands. A series of [1,2,3]thiadiazole benzylamides was found to be potent necroptosis inhibitors (called necrostatins). A structure-activity relationship study revealed that small cyclic alkyl groups (i.e. cyclopropyl) and 2,6-dihalobenzylamides at the 4- and 5-positions of the [1,2,3]thiadiazole, respectively, were optimal. In addition, when a small alkyl group (i.e. methyl) was present on the benzylic position all the necroptosis inhibitory activity resided with the (S)-enantiomer. Finally, replacement of the [1,2,3]thiadiazole with a variety of thiophene derivatives was tolerated, although some erosion of potency was observed.
