1176744-63-0 Usage
Uses
Used in Pharmaceutical Industry:
(2E,4E)-1-Chloro-4-(chloromethyl)-8,8-dimethyl-2,4-nonadien-6-yne is used as an intermediate in the synthesis of Terbinafine (T107500) derivatives for its role in the development of antifungal medications. Terbinafine is a widely used allylamine antifungal agent that targets the fungal cell membrane by inhibiting the enzyme squalene epoxidase, which is essential for fungal cell growth. The unique structural features of (2E,4E)-1-Chloro-4-(chloromethyl)-8,8-dimethyl-2,4-nonadien-6-yne allow for the creation of novel Terbinafine derivatives with potentially improved antifungal properties, such as enhanced efficacy, reduced side effects, or increased selectivity for specific fungal pathogens.
Check Digit Verification of cas no
The CAS Registry Mumber 1176744-63-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,6,7,4 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1176744-63:
(9*1)+(8*1)+(7*7)+(6*6)+(5*7)+(4*4)+(3*4)+(2*6)+(1*3)=180
180 % 10 = 0
So 1176744-63-0 is a valid CAS Registry Number.
1176744-63-0Relevant academic research and scientific papers
Novel stereoselective syntheses of (2E,4E)-4-(4,4-dimethylpent-2-ynylidene)-N1,N5-dimethyl-N1,N5-bis(naphthalen-1-ylmethyl)pent-2-ene-1,5-diamine
Colombo, Lino,Di Giacomo, Marcello,Serra, Massimo,Tambini, Simone M.
experimental part, p. 5838 - 5843 (2009/12/01)
We report two different synthetic approaches for the stereoselective synthesis of (2E,4E)-4-(4,4-dimethylpent-2-ynylidene)-N1,N5-dimethyl-N1,N5-bis(naphthalen-1-ylmethyl)pent-2-ene-1,5-diamine 1, an important im
