117675-21-5

Basic information

• Product Name: 3'-azido-3'-deoxy-5'-O-beta-glucopyranuronosylthymidine
• Synonyms: 3'-azido-3'-deoxy-5'-O-beta-glucopyranuronosylthymidine
• CAS NO: 117675-21-5
• Molecular Formula: C16H21N5O10
• Molecular Weight: 443.36544
• Mol File: 117675-21-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 3'-azido-3'-deoxy-5'-O-beta-glucopyranuronosylthymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-azido-3'-deoxy-5'-O-beta-glucopyranuronosylthymidine(117675-21-5)
• EPA Substance Registry System: 3'-azido-3'-deoxy-5'-O-beta-glucopyranuronosylthymidine(117675-21-5)

Safety Data

• Hazardous Substances Data: 117675-21-5(Hazardous Substances Data)

Upstream product

• 30516-87-1 3'-azido-2',3'-deoxythymidine 
• 1245697-26-0 UDP-glucuronic acid 

Relevant articles and documents

Validated assay for the evaluation of multiple glucuronidation activities in human liver microsomes via liquid chromatography-tandem mass spectrometry

A sensitive and high-throughput liquid chromatography-tandem mass spectrometry system was developed and validated for the simultaneous determination of major human hepatic UDP-glucuronyltransferase forms in human liver microsomes. The analytes were detected using a triple-quadrupole mass spectrometer equipped with an electrospray ionization source in the negative ion and selected reaction monitoring modes. The method provided satisfactory linear concentration range, accuracy, precision, and stability. The developed method was successfully applied to the enzyme kinetic study of estradiol-3-O-glucuronidation, 4-methylumbelliferone-O-glucuronidation, propofol-O-glucuronidation, and 3-azido-3-deoxythymidine glucuronidation in human liver microsomes.