117677-69-7Relevant academic research and scientific papers
Guanidyl drug lipid prodrug and its drug plastid
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Paragraph 0023-0026;0027, (2016/10/08)
The invention relates to a lipid prodrug of a drug containing guanidino and pharmacosome thereof. The lipid prodrug is a medicinal compound which is in covalent union with long-chain fatty acid with a single chain or double chains and contains guanidino. The pharmacosome is formed in such a way that the lipid prodrug disperses freely in a proper medium, is orderly arranged into a single-layer or double-layer structure, and is automatically assembled finally. The pharmacosome has biological targeting property, can effectively enhance the bioavailability of the drug and opens up a novel concept for solving the problems of poor transmembrane capability, low bioavailability and the like of a water soluble drug.
SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF
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Page/Page column 8-9, (2010/04/30)
The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted idebenone derivatives, methods of treating skin changes by topical application of these carb
