117679-89-7Relevant academic research and scientific papers
Spermexatin and Spermexatol: New Synthetic Spermidine-Based Siderophore Analogues
Sharma, Sushil K.,Miller, Marvin J.,Payne, Shelley M.
, p. 357 - 367 (1989)
Syntheses of hexanediamine-based dihydroxamate (Hexamate), spermidine-based trihydroxamate (Spermexatins), and spermidine-based mixed siderophore analogues (Spermexatols) are described.Key intermediates include the N-hydroxysuccinimide esters of various hydroxamic acids, e.g., malonohydroxamate, succinohydroxamate, and glutarohydroxamate.These intermediates were synthesized, characterized, and incorporated as the ligating chains on spermidine.Also, mixed iron chelating compounds (Spermexatols) with both catechol and hydroxamic acid side chains were synthesized.Thereagent carbobenzoxyimidazole was employed to distinguish between the primary and secondary amino groups of spermidine.The ability of these iron chelators to stimulate microbial growth is also described.
Antibody-catalyzed removal of the p-nitrobenzyl ester protecting group: The molecular basis of broad substrate specificity
Kurihara, Shinwa,Tsumuraya, Takeshi,Suzuki, Kayo,Kuroda, Masataka,Liu, Lidong,Takaoka, Yumiko,Fujii, Ikuo
, p. 1656 - 1662 (2007/10/03)
Antibody catalysts for the removal of the p-nitrobenzyl ester protecting group have been generated to accommodate a broad range of substrates. Antibody 7B9, which was elicited against p-nitrobenzyl phosphonate 1, catalyzed the hydrolyses of p-nitrobenzyl
Estrogen derivative having carriers to bone
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, (2008/06/13)
A novel estrogen derivative represented by the formula: STR1 is useful for treating or preventing diseases caused by estrogen deficiency.
