117686-70-1

Upstream product

• 117686-74-5 C₃₁H₂₅N₅O₈ 
• 117678-88-3 Phosphoric acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(4-methoxy-benzyloxy)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester; compound with triethyl-amine 

Relevant academic research and scientific papers

Durenesulfonic Acid Derivatives as New Condensing Reagents in the Nucleotide Synthesis Following the Triester Method

As shown by the synthesis of a series of ribonucleotide blocks durenesulfonyl chloride/1-methylimidazole and 1-(3-durenylsulfonyloxy)-6-nitrobenzotriazole (15) are adventageous alternative condensing reagents for the triester method.Hereby the 2'-OH function of the ribose is protected by the 4-methoxybenzyl group, which can be removed suitably by dry TFA/anisole instead of trityl tetrafluoroborate.