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1176869-86-5

4-(3-(3-methoxyphenyl)-5-(trimethylsilyl)thiophen-2-yl)benzonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1176869-86-5 Structure

  • Basic information

    1. Product Name: 4-(3-(3-methoxyphenyl)-5-(trimethylsilyl)thiophen-2-yl)benzonitrile
    2. Synonyms: 4-(3-(3-methoxyphenyl)-5-(trimethylsilyl)thiophen-2-yl)benzonitrile
    3. CAS NO:1176869-86-5
    4. Molecular Formula:
    5. Molecular Weight: 363.555
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1176869-86-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(3-(3-methoxyphenyl)-5-(trimethylsilyl)thiophen-2-yl)benzonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(3-(3-methoxyphenyl)-5-(trimethylsilyl)thiophen-2-yl)benzonitrile(1176869-86-5)
    11. EPA Substance Registry System: 4-(3-(3-methoxyphenyl)-5-(trimethylsilyl)thiophen-2-yl)benzonitrile(1176869-86-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1176869-86-5(Hazardous Substances Data)

1176869-86-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1176869-86-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,6,8,6 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1176869-86:
(9*1)+(8*1)+(7*7)+(6*6)+(5*8)+(4*6)+(3*9)+(2*8)+(1*6)=215
215 % 10 = 5
So 1176869-86-5 is a valid CAS Registry Number.

1176869-86-5Relevant articles and documents

Difunctionalisation of arenes and heteroarenes by directed metallation and sulfoxide-magnesium exchange

Melzig, Laurin,Rauhut, Christian B.,Naredi-Rainer, Nikolaus,Knochel, Paul

, p. 5362 - 5372 (2011/06/24)

The aryl sulfoxide moiety allows an expedient two-step difunctionalisation of readily available diaryl sulfoxides. Highly functionalised 1,2,4-trisubstituted arenes and difunctionalised heteroarenes (furans, thiophenes, benzofurans and pyridines) were prepared in a two-step sequence, triggered by an aryl sulfoxide group. In the first step, the sulfoxide moiety acts as a metallation-directing group, allowing smooth ortho-magnesiation with TMPMgCl.LiCl (TMP=tetramethylpiperidine). After a quenching reaction with an electrophile, the resulting sulfoxide is converted into a second magnesium reagent with iPrMgCl.LiCl (sulfoxide-magnesium exchange), which can be trapped with various electrophiles. Highly chemoselective TMPMgCl.LiCl and iPrMgCl.LiCl are compatible with a broad range of functional groups (e.g., F, Cl, CF 3, CN, CO2tBu, alkynyl, ethers, thioethers). Large-scale reactions (25-40 mmol) and the preparation of fully functionalised furans and thiophenes are also reported. Successful exchange: Highly functionalised 1,2,4-trisubstituted arenes and difunctionalised heteroarenes were prepared in a two-step sequence, triggered by an aryl sulfoxide group. The chemoselective reagents used, TMPMgCl.LiCl (TMP=tetramethylpiperidine) and iPrMgCl.LiCl, are compatible with a broad range of functional groups (see scheme; E=electrophile.)

2,3-Functionalization of furans, benzofurans and thiophenes via magnesiation and sulfoxide-magnesium exchange

Melzig, Laurin,Rauhut, Christian B.,Knochel, Paul

supporting information; experimental part, p. 3536 - 3538 (2009/12/02)

The use of TMPMgCl·LiCl and iPrMgCl·LiCl allows a sequential 2,3-difunctionalization of various 2-arylsulfinyl furans, thiophenes and benzofurans. Subsequent use of the same reagents permits a selective full functionalization of all 4 positions of the fur

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