117704-66-2

Basic information

• Product Name: Pradimicin B
• Synonyms: Pradimicin B;BMY-28634;N-[[[(5S)-5-[[4,6-Dideoxy-4-(methylamino)-β-D-galactopyranosyl]oxy]-5,6,8,13-tetrahydro-1,6β,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo[a]naphthacen]-2-yl]carbonyl]-D-alanine
• CAS NO: 117704-66-2
• Molecular Formula: C35H36N2O14
• Molecular Weight: 708.669
• Mol File: 117704-66-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 1013.1°Cat760mmHg
• Flash Point: 566.5°C
• Appearance: /
• Density: 1.65g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.736
• CAS DataBase Reference: Pradimicin B(CAS DataBase Reference)
• NIST Chemistry Reference: Pradimicin B(117704-66-2)
• EPA Substance Registry System: Pradimicin B(117704-66-2)

Safety Data

• Hazardous Substances Data: 117704-66-2(Hazardous Substances Data)

Usage

Definition

ChEBI: A member of the class of prodimicins that is isolated from the cultured broth of Actinomadura hibisca No. P157-2 (ATCC 53557).

InChI:InChI=1/C35H36N2O14/c1-10-6-17-22(28(42)19(10)33(46)37-11(2)34(47)48)21-15(27(41)32(17)51-35-31(45)30(44)24(36-4)12(3)50-35)9-16-23(29(21)43)26(40)14-7-13(49-5)8-18(38)20(14)25(16)39/h6-9,11-12,24,27,30-32,35-36,38,41-45H,1-5H3,(H,37,46)(H,47,48)/t11-,12-,24+,27+,30+,31-,32+,35+/m1/s1

Upstream product

• 117704-65-1 pradimicin A -5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo<α>naphthacen-2-yl>carbonyl>-D-alanine> 
• 150134-46-6 (R)-2-{[(5S,6S)-5-((2S,3R,4S,5R,6R)-3,4-Dihydroxy-6-methyl-5-methylamino-tetrahydro-pyran-2-yloxy)-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxo-5,6,8,13-tetrahydro-benzo[a]naphthacene-2-carbonyl]-amino}-propionic acid methyl ester 

Relevant articles and documents

Pradimicins l and fl, and derivatives thereof

The present invention relates to novel antifungal antibiotics herein designated as pradimicin L and pradimicin FL, and derivatives thereof. Pradimicins L and FL are produced by Actinomadura verrucosospora subsp. neohibisca strain R103-3, ATCC No. 53930.