117712-00-2

Basic information

• Product Name: (Z)-4-(4-isopropylphenyl)methylene-3-phenyl-5(4H)-isoxazolone
• CAS NO: 117712-00-2
• Molecular Weight: 291.349
• Mol File: 117712-00-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-4-(4-isopropylphenyl)methylene-3-phenyl-5(4H)-isoxazolone(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-(4-isopropylphenyl)methylene-3-phenyl-5(4H)-isoxazolone(117712-00-2)
• EPA Substance Registry System: (Z)-4-(4-isopropylphenyl)methylene-3-phenyl-5(4H)-isoxazolone(117712-00-2)

Safety Data

• Hazardous Substances Data: 117712-00-2(Hazardous Substances Data)

Upstream product

• 7713-79-3 3-phenyl-5-isoxazolone 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 1227841-04-4 (E)-benzaldehyde O-3-phenylpropioloyl oxime 
• 1227841-25-9 (E)-4-isopropylbenzaldehyde O-3-(4-methylphenyl)propioloyl oxime 

Downstream Products

• 117712-04-6 4-(4-isopropylphenyl)-1-methyl-2,5-diphenylpyrrole-3-carboxylic acid 

Relevant articles and documents

Gold-catalyzed cyclization and subsequent arylidene group transfer of O-propioloyl oximes

Gold-catalyzed cyclizations of O-propioloyl oximes via C-N bond formation followed by arylidene group transfer were successfully carried out to afford the corresponding 4-arylideneisoxazol-5(4H)-ones in good to excellent yields. As an example, (E)-benzaldehyde O-3-phenylpropioloyl oxime (1a) was reacted in acetonitrile at 25 °C in the presence of Au(PPh3)NTf2 (5 mol %) to give 4-benzylidene-3-phenylisoxazol-5(4H)-one (2a) in 90% yield. On the basis of crossover experiments, the arylidene "migration" was shown to proceed in an intermolecular manner.