1177141-67-1 Usage
Description
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride is a chemical compound with potent inhibitory action against casein kinase 1, particularly with respect to ATP, and a weaker effect on casein kinase 2 and other protein kinases. It is a beige solid with potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride is used as a pharmaceutical agent for its inhibitory action against casein kinase 1. Its ability to target this enzyme makes it a promising candidate for the development of drugs to treat diseases associated with abnormal kinase activity.
Used in Research Applications:
In the field of research, N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride is used as a research tool to study the role of casein kinase 1 in various biological processes. Its selective inhibition of this enzyme allows researchers to investigate its function and potential therapeutic targets.
Used in Drug Development:
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride is used in drug development as a lead compound for the creation of new drugs targeting casein kinase 1. Its potent inhibitory action and selectivity make it a valuable starting point for the design and synthesis of novel therapeutic agents.
Used in Chemical Synthesis:
In the chemical synthesis industry, N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride can be used as a building block or intermediate in the synthesis of other related compounds with potential applications in various fields, such as pharmaceuticals, agrochemicals, or materials science.
Biochem/physiol Actions
CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.
Check Digit Verification of cas no
The CAS Registry Mumber 1177141-67-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,7,1,4 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1177141-67:
(9*1)+(8*1)+(7*7)+(6*7)+(5*1)+(4*4)+(3*1)+(2*6)+(1*7)=151
151 % 10 = 1
So 1177141-67-1 is a valid CAS Registry Number.