117718-88-4

Basic information

• Product Name: Imidazo[1,2-a]pyrazin-8-amine (9CI)
• Synonyms: Imidazo[1,2-a]pyrazin-8-amine (9CI);Imidazo[1,2-a]pyrazin-8-amine
• CAS NO: 117718-88-4
• Molecular Formula: C₆H₆N₄
• Molecular Weight: 134.13864
• Product Categories: AMINETERTIARY
• Mol File: 117718-88-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.50±0.1 g/cm3(Predicted)
• PKA: 5.51±0.30(Predicted)
• CAS DataBase Reference: Imidazo[1,2-a]pyrazin-8-amine (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyrazin-8-amine (9CI)(117718-88-4)
• EPA Substance Registry System: Imidazo[1,2-a]pyrazin-8-amine (9CI)(117718-88-4)

Safety Data

• Hazardous Substances Data: 117718-88-4(Hazardous Substances Data)

Usage

General Description

Imidazo[1,2-a]pyrazin-8-amine (9CI) is a chemical compound with the molecular formula C8H7N5. It is a heterocyclic amine that contains both imidazole and pyrazine rings. Imidazo[1,2-a]pyrazin-8-amine (9CI) has potential pharmaceutical applications, particularly in the development of new drugs targeting specific biological processes. Imidazo[1,2-a]pyrazin-8-amine (9CI) is also used in research and development for its diverse chemical properties and potential therapeutic uses. However, further studies are needed to fully understand its pharmacological properties and potential applications in medicine.

Upstream product

• 63744-22-9 6,8-dibromoimidazo[1,2-a]pyrazine 
• 117718-84-0 PAB 12 

Downstream Products

• 1374986-65-8 3-(4-(cyclopropylsulfonyl)phenoxy)-N-(imidazo[1,2-a]pyrazin-8-yl)-5-((3-methylbut-2-en-1-yl)oxy)benzamide 

Relevant articles and documents

Synthesis and Antibronchospastic Activity of 8-Alkoxy- and 8-(Alkylamino)imidazopyrazines

Theophylline still occupies a dominant place in asthma therapy.Unfortunatly its adverse central nervous system (CNS) stimulant effects can dramatically limit its use, and adjustments in the dosage are often needed.We have synthesized a new series of imidazopyrazine derivatives which are much more potent bronchodilators than theophylline in vivo and do not exhibit the CNS stimulatory profile.In vitro studies on isolated rat uterus and guinea pig trachea confirm the high potentialities of these derivatives. 6-Bromo-8-(methylamino)imidazopyrazine-3-carbonitrile (23) is identified as the most potent compound of the series.As i n the case of theophylline, phosphodiesterase inhibition appears unlikely to be the unique mechanism of the action of this series of heterocycles.