1177251-07-8

Basic information

• Product Name: 1-{(4-benzyl-4H-1,2,4-triazol-3-yl)[4-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl}-4-cyclobutyl-1,4-diazepane
• Synonyms: 1-{(4-benzyl-4H-1,2,4-triazol-3-yl)[4-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl}-4-cyclobutyl-1,4-diazepane
• CAS NO: 1177251-07-8
• Molecular Weight: 498.695
• Mol File: 1177251-07-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{(4-benzyl-4H-1,2,4-triazol-3-yl)[4-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl}-4-cyclobutyl-1,4-diazepane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{(4-benzyl-4H-1,2,4-triazol-3-yl)[4-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl}-4-cyclobutyl-1,4-diazepane(1177251-07-8)
• EPA Substance Registry System: 1-{(4-benzyl-4H-1,2,4-triazol-3-yl)[4-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl}-4-cyclobutyl-1,4-diazepane(1177251-07-8)

Safety Data

• Hazardous Substances Data: 1177251-07-8(Hazardous Substances Data)

Upstream product

• 127406-11-5 4-(2-methyl-thiazol-4-yl)-benzaldehyde 
• 16227-13-7 4-benzyl-4H-1,2,4-triazole 

Relevant articles and documents

DIAZEPANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS

The invention relates to compounds of formula (I) wherein R1 to R8 and X1, X2 have the meaning as cited in the description and the claims. Said compounds are useful as Histamine H3 receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.