1177263-75-0Relevant academic research and scientific papers
Total synthesis of (-)-apratoxin A, 34-epimer, and its oxazoline analogue
Numajiri, Yoshitaka,Takahashi, Takashi,Doi, Takayuki
experimental part, p. 111 - 125 (2010/07/06)
A concise and convergent total synthesis of the highly cytotoxic marine natural product apratoxin A is accomplished by an 18-step linear sequence. The high sensitivity of the thiazoline, bearing an adjacent β-hydroxyl group at the C35-position, results in
