117733-36-5Relevant articles and documents
1,3-Dipolar Cycloaddition Reactions of 1-Aryl-N-methyl-2-(1H-azol-1-yl)-ethanimine N-Oxides to Olefins
Mullen, George B.,Bennett, Grace A.,Swift, Patricia A.,Marinyak, David M.,Dormer, Peter G.,Georgiev, Vassil St.
, p. 105 - 107 (2007/10/02)
The regio- and stereoselectivity of the 1,3-dipolar cycloaddition reaction of 1-aryl-N-methyl-2-(1H-azol-1-yl)ethanimine N-oxides 6 to monosubstituted olefins 7 were investigated.The reaction is regioselective, leading to the corresponding C-5 substituted isoxazolidines 8/9 as cis/trans diastereomeric mixtures.The cis isomers, which are the predominant species of the mixtures, are readily separated by flash chromatography on neutral silica gel.
Studies on antifungal agents 30. Novel substituted 3-(2-furanyl)-3-(1H-imidazol-1-ylmethyl)-2-methyl-5-phenyl(or phenyloxymethyl)-isoxazolidines
Bennett, Grace A.,Mullen, George B.,Mitchell, Jeffrey T.,Jones, Wendy E.,Allen, Stanley D.,et al.
, p. 579 - 584 (2007/10/02)
The synthesis of a novel class of antifungal agents, the 3-(2-furanyl)-3-(1H-imidazol-1-ylmethyl)-2-methyl-5-phenyl(or phenoxymethyl)isoxazolidines (10-15) is described.When tested in vitro, derivatives 10-15 exerted a potent antifungal activity against d
