1177357-94-6 Usage
Uses
Used in Pharmaceutical Industry:
(3α)-Allopregnanolone Sulfate PyridiniuM Salt is used as a pharmaceutical agent for its neuroactive properties. It modulates GABAA receptors, which play a crucial role in the central nervous system, and has potential therapeutic applications in treating neurological disorders and anxiety-related conditions.
Used in Research Applications:
(3α)-Allopregnanolone Sulfate PyridiniuM Salt is used as a research tool for studying the effects of neurosteroids on GABAA receptors and their role in various physiological and pathological processes. It helps researchers gain insights into the mechanisms underlying the modulation of these receptors and the development of potential therapeutic agents.
Used in Drug Development:
(3α)-Allopregnanolone Sulfate PyridiniuM Salt is used in drug development as a lead compound for the design and synthesis of new drugs targeting GABAA receptors. Its potent modulatory effects on these receptors make it a promising candidate for the development of medications for various neurological and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 1177357-94-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,7,3,5 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1177357-94:
(9*1)+(8*1)+(7*7)+(6*7)+(5*3)+(4*5)+(3*7)+(2*9)+(1*4)=186
186 % 10 = 6
So 1177357-94-6 is a valid CAS Registry Number.
1177357-94-6Relevant academic research and scientific papers
Kapras, Vojtech,STastna, Eva,Chodounska, Hana,Pouzar, Vladimir,Kristofikova, Zdena
, p. 643 - 650 (2009)
Sulfamoyl chloride was used for the preparation of 3a- and 3β-sulfamates of steroids: 20-oxo-5α-pregnan-3α-yl sulfamate (4), 20-oxo-5α-pregnan-3β-yl sulfamate (5), 20-oxo-5β-pregnan- 3α-yl sulfamate (7), and 20-oxo-5β-pregnan-3β-yl sulfamate (9) from the
Synthesis of C3, C5, and C7 pregnane derivatives and their effect on NMDA receptor responses in cultured rat hippocampal neurons
Stastna, Eva,Chodounska, Hana,Pouzar, Vladimir,Kapras, Vojtech,Borovska, Jirina,Cais, Ondrej,Vyklicky Jr., Ladislav
experimental part, p. 256 - 263 (2009/04/14)
The synthesis of several novel 5α- and 5β-20-oxo-pregnane derivatives substituted in the position 3 and 7 of the steroid skeleton is described. Activity of synthesized compounds was studied in voltage-clamped cultured rat hippocampal neurons. Substituted
