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117736-74-0

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117736-74-0 Usage

Uses

3-(Methylthio)-1H-pyrazol-5-amine is a reagent used in the synthesis and evaluation of 2-(α-arylalkylamino)-4-(pyrazolylamino)pyrimidines as potent inhibitors of Trk kinases.

Check Digit Verification of cas no

The CAS Registry Mumber 117736-74-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,7,3 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 117736-74:
(8*1)+(7*1)+(6*7)+(5*7)+(4*3)+(3*6)+(2*7)+(1*4)=140
140 % 10 = 0
So 117736-74-0 is a valid CAS Registry Number.

117736-74-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(Methylthio)-1H-pyrazol-5-amine

1.2 Other means of identification

Product number -
Other names 3-methylsulfanyl-1H-pyrazol-5-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:117736-74-0 SDS

117736-74-0Downstream Products

117736-74-0Relevant articles and documents

1H-PYRAZOLO [3, 4-B] PYRIDINE COMPOUNDS FOR INHIBITING RAF KINASE

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Page/Page column 54, (2011/04/14)

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. [FORMULA I]

PYRAZOLE [3, 4-B] PYRIDINE RAF INHIBITORS

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Page/Page column 109, (2009/10/22)

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSYNE KINASES

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Page/Page column 117, (2008/06/13)

Compounds of formula (I): and their use in the inhibition of Trk activity are described.

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