1177408-14-8

Basic information

• Product Name: (isoquinolin-1-yl)(2-trifluoromethylphenyl)methanone
• Synonyms: (isoquinolin-1-yl)(2-trifluoromethylphenyl)methanone
• CAS NO: 1177408-14-8
• Molecular Weight: 301.268
• Mol File: 1177408-14-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (isoquinolin-1-yl)(2-trifluoromethylphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (isoquinolin-1-yl)(2-trifluoromethylphenyl)methanone(1177408-14-8)
• EPA Substance Registry System: (isoquinolin-1-yl)(2-trifluoromethylphenyl)methanone(1177408-14-8)

Safety Data

• Hazardous Substances Data: 1177408-14-8(Hazardous Substances Data)

Upstream product

• 1198-30-7 1-isoquinolinecarbonitrile 
• 392-83-6 o-trifluoromethylphenyl bromide 

Relevant articles and documents

Synthesis of quinolinyl and isoquinolinyl phenyl ketones as novel agonists for the cannabinoid CB2 receptor

A series of quinolinyl and isoquinolinyl phenyl ketones was synthesized and their CB2 receptor-dependent G-protein activities were determined using the [35S]GTPγS binding assay. Both quinoline and isoquinoline derivatives exhibited similar CB2 receptor agonist activity, the most potent ligands being the 2-(Me2N)-phenyl substituted derivatives, which were also full agonists at the CB2-receptor.