1177454-60-2Relevant articles and documents
Asymmetric synthesis of 2-Substituted 3-amino-4-cyanopyrroles via a two-step procedure consisting of a SNV reaction on ethoxymethylenemalononitrile followed by a Thorpe-Ziegler cyclization
Botsi, Sofia,Tsolomiti, Georgia,Hamilakis, Stylianos,Tsolomitis, Athanase
, p. 233 - 236 (2008)
An asymmetric synthesis of 2-Substituted 3-amino-4-cyanopyrroles via a two-step procedure consisting of a nucleophilic vinylic substitution (S NV), of ethoxymethylenemalononitrile (EMM), with optically pure α-amino acid esters, resulting to the corresponding aminomethylemalononitriles, followed by a Thorpe-Ziegler cyclization, is described.