117751-84-5

Upstream product

• 1152-62-1 Cbz-Met-OH 
• 16874-01-4 benzyl (S)-1-(tert-butoxycarbonyl)-3-(methylthio)propylcarbamate 

Downstream Products

• 117751-86-7 tert-butyl (S)-2-(((benzyloxy)carbonyl)amino)but-3-enoate 
• 117751-80-1 2(S)-tert-butyl 2-N-benzyloxycarbonylamino-3,4-epoxybutanoate 
• 117751-75-4 2'(R),3'(S)-N-(2-acetoxy-3-benzyloxycarbonylamino-3-tert-butoxycarbonylpropyl)N-tert-butoxycarbonylglycine tert-butyl ester 
• 117772-22-2 2'(R),3'(S)-N-(3-benzyloxycarbonylamino-3-tert-butoxycarbonyl-2-hydroxypropyl)N-tert-butoxycarbonylglycine tert-butyl ester 
• 117751-74-3 2'(R),3'(S)-N-(3-benzyloxycarbonylamino-3-tert-butoxycarbonyl-2-hydroxypropyl)glycine tert-butyl ester 
• 68366-38-1 4-(methylsulfinyl)-2-[[(phenylmethoxy)carbonyl]amino]-(2S)-butanoic acid 
• 70982-53-5 (S)-2-amino-3-butenoic acid 

Relevant academic research and scientific papers

Suzuki-Miyaura cross-coupling reaction of monohalopyridines and L-aspartic acid derivative

Suzuki-Miyaura cross-coupling reaction of halogenated pyridines and a borated L-aspartic acid derivative was conducted. The reactivity of chloro-, bromo-, and iodo-pyridines with substituents at the C2, C3, and C4 positions was investigated. Electron dens

Deprotection of t-butyl esters of amino acid derivatives by nitric acid in dichloromethane

The extension of the deprotection procedure of t-butylated carboxyl function using HNO3 in CH2Cl2 to a number of appropriately selected N-Z- derivatives of natural amino acid esters was investigated. The method was found to work effectively with alanine, phenylalanine, serine and the dipeptide aspartame, but the reagent brought about a number of unwanted transformations with tyrosine, methionine and tryptophan. Suitable protection of functions present in the latter ones allowed selective ester dealkylation, but tyrosine underwent unavoidable fast preliminary ring nitration. 2000 Elsevier Science Ltd.