117751-90-3

Upstream product

• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 95445-79-7 3-methyl 5-(1-methylethyl) 4-(3-chloro-6-fluoro-2-(trifluoromethyl)phenyl)-2-(fluoromethyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate 

Relevant academic research and scientific papers

A Novel, Base-induced Fragmentation of Hantzsch-type 4-Aryl-1,4-dihydropyridines

Hantzsch-type 1,4-dihydropyridine derivatives substituted with highly electron-deficient aryl groups in the 4-position, on treatment with a variety of basic reagents in non-hydroxylic solvents, undergo an unexpected and ready scission of the inter-ring bond to give the corresponding 4-unsubstituted pyridine and an arene derived from the original 4-substituent.The scope of the reaction has been investigated and possible mechanisms are discussed.