117751-98-1Relevant academic research and scientific papers
A Novel, Base-induced Fragmentation of Hantzsch-type 4-Aryl-1,4-dihydropyridines
McInally, Thomas,Tinker, Alan C.
, p. 1837 - 1844 (2007/10/02)
Hantzsch-type 1,4-dihydropyridine derivatives substituted with highly electron-deficient aryl groups in the 4-position, on treatment with a variety of basic reagents in non-hydroxylic solvents, undergo an unexpected and ready scission of the inter-ring bond to give the corresponding 4-unsubstituted pyridine and an arene derived from the original 4-substituent.The scope of the reaction has been investigated and possible mechanisms are discussed.
