117752-82-6 Usage
Description
(S)-3-Amino-gamma-butyrolactone hydrochloride is a chemical compound predominantly utilized in scientific and pharmaceutical research. It is a derivative of gamma-butyrolactone, a versatile intermediate compound frequently employed to synthesize other chemicals. (S)-3-Amino-gamma-butyrolactone hydrochloride is characterized by the nucleophilic nature of its amino group, which makes it an excellent building block in organic chemistry, capable of participating in a variety of chemical reactions such as condensation, substitution, and reduction. As a hydrochloride, it is typically found in a solid state and is easily soluble in water, facilitating its use in laboratory settings. However, it is important to handle this compound with care, as the full extent of its effects on human health and the environment is not yet fully understood.
Uses
Used in Scientific Research:
(S)-3-Amino-gamma-butyrolactone hydrochloride is used as a research compound for its versatile chemical properties. Its amino group's nucleophilic nature allows it to participate in various chemical reactions, making it a valuable building block in organic chemistry.
Used in Pharmaceutical Research:
(S)-3-Amino-gamma-butyrolactone hydrochloride is used as a pharmaceutical intermediate for the synthesis of other compounds. Its ability to engage in condensation, substitution, and reduction reactions makes it a useful component in the development of new drugs and pharmaceutical products.
Used in Organic Chemistry:
(S)-3-Amino-gamma-butyrolactone hydrochloride is used as a reagent in organic chemistry for its ability to facilitate a range of chemical reactions. Its solid state and solubility in water make it an easily handled compound in laboratory settings, contributing to its utility in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 117752-82-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,7,5 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 117752-82:
(8*1)+(7*1)+(6*7)+(5*7)+(4*5)+(3*2)+(2*8)+(1*2)=136
136 % 10 = 6
So 117752-82-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H7NO2.ClH/c5-3-1-4(6)7-2-3;/h3H,1-2,5H2;1H/t3-;/m0./s1
117752-82-6Relevant articles and documents
Convenient synthesis of 3-(S)-amino-γ-butyrolactone
Sibrian-Vazquez, Martha,Spivak, David A.
, p. 1105 - 1106 (2002)
An efficient two step conversion of N-t-Boc-L-aspartic acid β-benzyl ester to enantiopure 3-(S)-amino-γ-butyrolactone is described. In this route, chemoselective reduction of the α-carboxylic group in the starting material via a mixed anhydride with NaBH4 afforded the corresponding alcohol in 95% yield without any loss of the optical purity. Subsequent acidic hydrolysis of the N-protected β-amino alcohol not only deprotected the amino group, but also produced the desired γ-lactone in 98% yield with complete retention of the optical activity.
CRYSTALLINE FORMS OF A PYRROLIDONE DERIVATIVE USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE AND PREPARATION THEREOF
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Page/Page column 19; 20, (2015/05/19)
The present invention provides processes to manufacture crystalline N-[(3S)-1-[4-[(3-fluorophenyl)methoxy]phenyl]-5-oxo-pyrrolidin-3-yl]acetamide. Also disclosed are polymorphic forms of said compound as well as compounds useful as intermediates in the methods of the invention.
Synthesis of enantiomerically pure β-amino-α-methylene-γ-butyrolactones by way of ozonolysis of aromatic α-amino acids
Hvidt, Torsten,Szarek, Walter A.,Maclean, David B.
, p. 779 - 782 (2007/10/02)
The (R) and (S) isomers of β-amino-α-methylene-γ-butyrolactone hydrochloride (4-amino-dihydro-3-methylene-2(3H)-furanone hydrochloride) have been synthesized from (R)- and (S)-tryptophan, respectively.A key step is the ozonolysis of N,O-diacetyl-2-amino-3-(3'-indolyl)-1-propanol. (S)-β-Amino-α-methylene-γ-butyrolactone hydrochloride has been synthesized also by an analogous route starting with (S)-phenylalanine.