117767-17-6Relevant articles and documents
Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis
Steffan, Robert J.,Matelan, Edward,Ashwell, Mark A.,Moore, William J.,Solvibile, William R.,Trybulski, Eugene,Chadwick, Christopher C.,Chippari, Susan,Kenney, Thomas,Eckert, Amy,Borges-Marcucci, Lisa,Keith, James C.,Xu, Zhang,Mosyak, Lydia,Harnish, Douglas C.
, p. 6435 - 6438 (2007/10/03)
Pathway-selective ligands for the estrogen receptor (ER) inhibit NF-κB-mediated inflammatory gene expression causing a reduction of cytokines, chemokines, adhesion molecules, and inflammatory enzymes. SAR development of a series of 4-(indazol-3-yl)phenols
