117768-25-9Relevant academic research and scientific papers
Kinetic H/D Isotope Effect of the Photooxidation of 3,5-Dimethyl-1,1-dioxo-2-(p-tolyl)-1,2-thiazine by Singlet Oxygen
Fanghaenel, E.,Bode, B.,Bedemann, K.-H.,Radeglia, R.
, p. 79 - 83 (2007/10/02)
The hydrogen atoms of the thiazine ring and of the methyl groups of 3,5-dimethyl-1,1-dioxo-2-(p-tolyl)-1,2-thiazine 1a can be exchanged by deuterium in basic or acidic deutero methanol (CH3OD).In CD3OD/D2SO4 the rate of the H/D-exchange of the different protons of 1a was determined by 1H-n.m.r. spectroscopy.A kinetic isotope effect of 1.5-1.8 was determined from the rate of the oxygen consumption and also by using a competitive method.The results are in accordance with an "ene" reaction of 1a with singlet oxygen.
