117830-20-3Relevant academic research and scientific papers
THIAZOLIDINECARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR THERAPEUTIC USES
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, (2008/06/13)
Thiazolidinecarboxylic acid amides having combined antiallergic and antiasthmatic activities with an antagonist activity against platelet Activating Factor and having the following general formula (I) STR1
Heteroarylcarboxamide derivatives, process for preparing the same and pharmaceutical composition containing the same
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, (2008/06/13)
Heteroarylcarboxamide derivatives of the formula I: STR1 wherein A means an alkylene group, X means 2 or 2 in which Ph means phenyl and Het means a group of the formulas: STR2 in which Y means nitrogen atom or =CH--, R1 means hydroxy, a lower alkoxy or mercapto, R2 means hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, nitro or cyano, R3 means a lower alkyl group, provided that R2 is attached at the 7-position when Y means nitrogen atom, or physiologically acceptable salts thereof, a process for preparing the same and a pharmaceutical composition containing the same as an active ingredient. The compounds of the present invention and salts thereof show an excellent antiallergic activity and thus are useful for the prophylaxis and treatment of allergic diseases.
