117832-17-4

Basic information

• Product Name: 2-IODO-4,5-DIMETHYLBENZENAMINE
• Synonyms: 4,5-DIMETHYL-2-IODOANILINE;2-IODO-4,5-DIMETHYLBENZENAMINE;2-iodo-4,5-dimethylaniline
• CAS NO: 117832-17-4
• Molecular Formula: C₈H₁₀IN
• Molecular Weight: 247.08
• Mol File: 117832-17-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 283.3 °C at 760 mmHg
• Flash Point: 125.1 °C
• Appearance: /
• Density: 1.688 g/cm³
• CAS DataBase Reference: 2-IODO-4,5-DIMETHYLBENZENAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODO-4,5-DIMETHYLBENZENAMINE(117832-17-4)
• EPA Substance Registry System: 2-IODO-4,5-DIMETHYLBENZENAMINE(117832-17-4)

Safety Data

• Hazardous Substances Data: 117832-17-4(Hazardous Substances Data)

Usage

General Description

2-Iodo-4,5-Dimethylbenzenamine is a chemical compound classified under the group of organoiodine compounds, specifically an iodobenzene. This particular compound involves an iodine atom bonded to a complex molecular structure containing a benzene, which is an aromatic ring, substituted with two methyl groups and an amine group (NH2). Its molecular formula is C8H10IN. The presence of iodine makes it significant for use in organic synthesis. It appears as a crystalline solid. Like many other chemicals, care must be taken during its handling due to potential hazards.

Upstream product

• 95-64-7 4-amino-o-xylene 

Downstream Products

• 1189351-11-8 C₆H₁₅N*C₉H₁₀INS₂ 
• 1269795-88-1 (S)-methyl 2-(5,6-dimethylbenzo[d]thiazol-2-ylamino)-3-phenylpropanoate 
• 1280563-43-0 C₁₃H₁₉NO₃ 
• 1280563-56-5 C₁₅H₁₈F₃NO₄ 
• 1280563-61-2 C₃₆H₃₆F₃NO₆ 
• 1280563-73-6 C₄₅H₅₃F₃N₃O₇P 
• 1404532-72-4 {3-[4-(4-butyryl-5-methyl-pyrazol-1-yl)phenylcarbamoyl]-5,6-dimethyl-indol-1-yl}acetic acid methyl ester 
• 1404529-46-9 {3-[4-(4-butyryl-5-methyl-pyrazol-1-yl)phenylcarbamoyl]-5,6-dimethyl-indol-1-yl}acetic acid 
• 1404535-55-2 N-[4-(4-butyryl-5-methyl-pyrazol-1-yl)phenyl]-1-dimethylcarbamoylmethyl-5,6-dimethyl-1H-indole-3-carboxamide 
• 1404535-61-0 [4-(4-butyryl-5-methyl-pyrazol-1-yl)phenyl]-5,6-dimethyl-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide hydrochloride 
• 1303996-82-8 2-(benzylthio)-5,6-dimethylbenzo[d]thiazole 
• 875930-14-6 4,5-dimethyl-2-(phenylethynyl)aniline 
• 887903-00-6 4,5-dimethyl-2-(trimethylsilylethynyl)aniline 

Relevant articles and documents

New Indolo[3,2-b]indole based small organic molecules for Organic Thin Film Transistors (OTFTs): A combined experimental and DFT Study

Synthesis of new indolo[3,2-b]indoles (5a- 5j) in presence of Ag-doped ZnO and (Diacetoxyiodo) benzene system under visible-light have been reported. All the new fused linear heterocyclic indolo[3,2-b]indole systems (5a- 5j) thoroughly characterized by spectroscopic methods like mass, UV-visible, NMR and C, H, N elemental analysis. Further, their photophysical properties were carried out by combined experimental and theoretical studies. Thermogravimetric studies are carried out to confirm the thermal stability of molecules. The frontier molecular orbitals of molecules are characterized with the help of cyclic voltammetry. Additionally, the compounds of series 5 were used for the fabrication of organic thin-film transistors, which indicated the hole mobilities in the range of 0.11 – 0.85 cm2/Vs and with on/off ratio 105 on ODTS-SiO2 substrate at 50 °C and are also supported by DFT studies.

PFKFB3 INHIBITORS AND THEIR USES

This disclosure relates to new phthalimide and isoindolinone derivatives and other PFKFB3 inhibitors for use in the treatment of diseases. The invention further relates to pharmaceutical compositions containing such PFKFB3 inhibitors, methods of preparation thereof, methods for their use as therapeutic agents, and methods of preparation of a medicament for use in therapy, as well as kits and other inventiions comprising such PFKFB3 inhibitors. These PFKFB3 inhibitors are useful for the treatment and prophylaxis of cancer, neurodegenerative diseases, autoimmune diseases, inflammatory disorders, multiple sclerosis, metabolic diseases, inhibition of angiogenesis and other diseases and conditions, where the modulation of PFKFB3 and/or PFKFB4 has beneficial effect as well as neuroprotection.

NOVEL RECYCLABLE IODINATING AGENT AND ITS APPLICATIONS

The present invention provides a novel recyclable catalysts of formula A, [Formula A should be inserted here] wherein X is selected from the group consisting of [Formula should be inserted here] The present invention also provides a novel recyclable iodinating agent of formula I, II or III and a process for the synthesis thereof. [ Formula I, II & III should be inserted here] Further, the present invention provides a process of halogenation of amines and heterocyclic compounds by employing recyclable catalyst of formula (I).