1178513-61-5

Basic information

• Product Name: (2-bromo-4-methoxyphenoxy)(tert-butyl)diphenylsilane
• Synonyms: (2-bromo-4-methoxyphenoxy)(tert-butyl)diphenylsilane
• CAS NO: 1178513-61-5
• Molecular Weight: 441.44
• Mol File: 1178513-61-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-bromo-4-methoxyphenoxy)(tert-butyl)diphenylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-4-methoxyphenoxy)(tert-butyl)diphenylsilane(1178513-61-5)
• EPA Substance Registry System: (2-bromo-4-methoxyphenoxy)(tert-butyl)diphenylsilane(1178513-61-5)

Safety Data

• Hazardous Substances Data: 1178513-61-5(Hazardous Substances Data)

Upstream product

• 17332-11-5 2-bromo-4-methoxyphenol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1178513-85-3 6-tert-butyl-2-methoxy-6-phenyl-6H-dibenzo[c,e][1,2]oxasiline 

Relevant articles and documents

TBDPS and Br-TBDPS protecting groups as efficient aryl group donors in Pd-catalyzed arylation of phenols and anilines

(Chemical Equation Presented) It is shown that the TBDPS protecting group can serve as an efficient phenyl group donor for o-bromophenols via Pd-catalyzed C-H arylation followed by a routine TBAF deprotection of the resulting silacycles. Employment of the newly designed Br-TBDPS protecting group in the same sequence allows for a facile introduction of a phenyl group at the ortho position of phenols and anilines. Alternatively, switching desilylation to oxidation in the last step allows the conversion of forming silacycles into valuable o-biphenols.