1178533-21-5Relevant articles and documents
Facile synthesis of fluorinated 1-desazapurines
Iaroshenko, Viktor O.,Sevenard, Dmitri V.,Volochnyuk, Dmitriy M.,Wang, Yan,Martiloga, Alexander,Tolmachev, Andrei O.
scheme or table, p. 1865 - 1875 (2009/12/30)
A preparative approach towards 1-desazapurines, starting from 4(5)-aminoimidazoles and polyfluoroalkyl-containing 1,3-CCC-biselectrophiles was developed. As a result, a set of fluorinated 1-desazapurines was synthesized. Additionally, a synthetic route to 1-desazapurines bearing a sugar-mimicking group is proposed. Georg Thieme Verlag Stuttgart.