117856-52-7

Upstream product

• 13683-41-5 1-bromo-1-(trimethylsilyl)ethene 
• 86486-85-3 3-trimethylsilylbut-3-en-1-ol 
• 104124-04-1 4-(dimethyl-t-butylsilyloxy)-2-trimethylsilylbut-1-ene 
• 754-05-2 ethenyltrimethylsilane 
• 117856-60-7 1-(dimethyl-t-butylsilyloxy)-3-iodo-3-trimethylsilyl-4-(p-tolylsulphonyl)butane 
• 42492-87-5 N,N'-dibenzylpiperazine-2,5-dione 
• 104124-05-2 (1Z)-4-(dimethyl-t-butylsilyloxy)-2-trimethylsilyl-1-(p-tolylsulphonyl)but-1-ene 

Relevant academic research and scientific papers

Synthetic Studies on Bicyclomycin and its Analogues. Part 1. Synthesis of Substituted 2-Oxa-8,10-diazabicyclodecanes

Methods have been developed for formation of the eight-membered oxygen-containing ring system (2) present in the antibiotic bicyclomycin.The procedure starts with N,N'-disubstituted piperazine-2,5-diones or the corresponding mono imino ethers.A new method is based on the oxidation of the mono imino ethers using 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) as oxidant: the bis imino ethers gave pyrazines under these conditions, whilst the parent piperazinedione proved to be unreactive.