117860-49-8

Basic information

• Product Name: 3,5-diisopropenyl-2,6-dimethylpyridine
• CAS NO: 117860-49-8
• Molecular Weight: 187.285
• Mol File: 117860-49-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-diisopropenyl-2,6-dimethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diisopropenyl-2,6-dimethylpyridine(117860-49-8)
• EPA Substance Registry System: 3,5-diisopropenyl-2,6-dimethylpyridine(117860-49-8)

Safety Data

• Hazardous Substances Data: 117860-49-8(Hazardous Substances Data)

Upstream product

• 1149-24-2 2,6-dimethyl-pyridine-3,5-dicarboxylic acid diethyl ester 
• 117860-48-7 3,5-bis<2-(2-hydroxypropyl)>-2,6-lutidine 

Relevant articles and documents

Effect of Pressure on the Rate of Methylation of a Buttressed Pyridine

3,5-Di-tert-butylpyridine (3) and 2,6-dimethyl-3,5-di-tert-butylpyridine (4) have been synthesized.Compound 3 was obtained by means of acid-catalyzed condensation of N-tert-butylmethanimine with N-(3,3-dimethylbut-1-enyl)piperidine; this reaction also furnished 3,5-di-neo-hexylpyridine (7).Compound 4 was prepared from Hantzsch's ester 8, by an application of the Schleyer method for converting ester groups into tert-butyl functions.The methylation rates of 3 and 4 in acetonitrile at 45 deg C were compared with those of pyridine and 2,6-lutidine.It was deduced that the two tert-butyl groups cause a retardation by buttressing by a factor of 57.Comparison with the known rates of 5- and 3-tert-butyl-2-methylpyridines (1 and 2, respectively) shows that the buttressing effect is minimized in the latter case by bending of the incipient N-methyl bond.The rates were also measured under pressure; the activation volumes follow the normal trend expected of directly hindered Menschutkin reactions.