1178966-47-6

Basic information

• Product Name: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl) acetic acid hydrochloride
• Synonyms: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl) acetic acid hydrochloride
• CAS NO: 1178966-47-6
• Molecular Weight: 622.656
• Mol File: 1178966-47-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl) acetic acid hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl) acetic acid hydrochloride(1178966-47-6)
• EPA Substance Registry System: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl) acetic acid hydrochloride(1178966-47-6)

Safety Data

• Hazardous Substances Data: 1178966-47-6(Hazardous Substances Data)

Upstream product

• 151767-02-1 Montelukast sodium 
• 158966-92-8 montelukast 

Downstream Products

• 158966-92-8 montelukast 

Relevant articles and documents

PROCESS FOR THE PURIFICATION OF MONTELUKAST BY THE PREPARATION OF ACID ADDITION SALTS AND TERT-AMYLAMINE SALT

The present invention relates to processes for the purification of montelukast by the preparation of acid addition salts and tert-amylamine salt. The preparation of acid addition salts is very efficient and does not lead to the increase of impurities arising from the dehydration of the tertiary alcohol, such as styrene impurity, while the use of tert-amylamine salt highly reduces the content of styrene impurity and montelukast sulfoxide.