1179466-76-2Relevant academic research and scientific papers
2-Aryl-5-arylsulfanyl-1,3-oxazole-4-carboxylic acids and their derivatives
Pil'o,Prokopenko,Brovarets,Drach
, p. 1345 - 1350 (2010)
A convenient preparative procedure has been developed for the synthesis of previously unknown 2- aryl-5-arylsulfanyl-1,3-oxazole-4-carboxylic acids and their functional derivatives from accessible multicenter substrates of the general formula Cl2C=C(NHCOR)C(O)OMe. The products turned out to be suitable for various subsequent transformations. Some oxazole-4-carboxylic acid hydrazide derivatives containing a substituted oxazol-5-yl fragment at the N2 atom in the hydrazine moiety underwent recyclization on heating in acetic acid; as a result, one oxazole ring was converted into 1,3,4-oxadiazole. Pleiades Publishing, Ltd., 2010.
