1179476-64-2

Upstream product

• 26510-95-2 ethyl 4-Bromobenzoylacetate 

Downstream Products

• 1179476-73-3 C₂₁H₂₈BrFN₂O₇ 
• 1300014-02-1 (2S,3S)-ethyl 2-(4-bromobenzoyl)-3-(tert-butoxycarbonylamino)-2-fluoro-3-(2-furanyl)propanoate 
• 1260108-95-9 ditert-butyl (R)-1-(1-(4-bromophenyl)-3-ethoxy-2-fluoro-1,3-dioxopropan-2-yl)hydrazine-1,2-dicarboxylate 

Relevant academic research and scientific papers

Synthesis of monofluorooxazoles with quaternary C-F centers through photoredox-catalyzed radical addition of methylene-2-oxazolines

A novel photoredox-catalyzed radical addition of methylene-2-oxazolines has been developed under visible light irradiation to synthesize monofluorooxazoles with a quaternary carbon center using 2-bromo-2-fluoro-3-oxo-3-phenylpropionates as radical source. This method with a simple protocol, scalability and high yield offers a facile path to get diverse monofluorinated oxazoles with quaternary C-F centers, which are a class of highly valuable motifs and synthons.