117979-63-2

Upstream product

• 3775-01-7 5-benzylidenehydantoin 

Downstream Products

• 117979-65-4 4-[2,5-Dioxo-imidazolidin-(4Z)-ylidenemethyl]-N,N-dimethyl-benzenesulfonamide 
• 117979-66-5 4-[2,5-Dioxo-imidazolidin-(4Z)-ylidenemethyl]-N,N-diethyl-benzenesulfonamide 
• 117979-87-0 4-[2,5-Dioxo-imidazolidin-(4Z)-ylidenemethyl]-benzenesulfonyl azide 
• 331628-15-0 2-{4-[2,5-Dioxo-imidazolidin-(4Z)-ylidenemethyl]-benzenesulfonylamino}-3-methyl-butyric acid 
• 331628-10-5 {4-[2,5-Dioxo-imidazolidin-(4Z)-ylidenemethyl]-benzenesulfonylamino}-acetic acid 
• 331628-17-2 2-{4-[2,5-Dioxo-imidazolidin-(4Z)-ylidenemethyl]-benzenesulfonylamino}-4-methyl-pentanoic acid 
• 331628-13-8 3-{4-[2,5-Dioxo-imidazolidin-(4Z)-ylidenemethyl]-benzenesulfonylamino}-propionic acid 

Relevant academic research and scientific papers

Synthesis of some novel benzylidenehydantoins: Amino acids derivatives

5-Benzylidenehydantoin reacts with chlorosulfonic acid to give the corresponding p-sulfonyl chloride. Condensation of the latter with amino acids leads to sulfonylamino acid derivatives, which on coupling with glycine methyl ester hydrochloride in THF-Et

REACTIONS OF CHLOROSULFONYLBENZYLIDENE HYDANTOINS

5-(Benzylidene- and o-chlorobenzylidene-) and cinnamylidene-hydantoins reacted with chlorosulfonic acid to give the corresponding p-sulfonyl chlorides (1, 35, 44).These were converted into 49 derivatives by reaction with amines, hydrazines and azide ion.