1179854-50-2Relevant academic research and scientific papers
Cyclometallated platinum(II) compounds with imine ligands derived from amino acids: Synthesis and oxidative addition reactions
Rodríguez, Judit,Zafrilla, Javier,Albert, Joan,Crespo, Margarita,Granell, Jaume,Calvet, Teresa,Font-Bardia, Mercè
, p. 2467 - 2475 (2009/12/01)
The reactions of [PtMe2(μ-SMe2)]2 with imines 4-ClC6H4CH{double bond, long}NCHRCO2Me (R = H (1a), Me (1b), iPr (1c), CH2C6H4(4'-OH) (1d), C6H5 (1e), CH2C6H5(1f)) derived from natural amino acids produced under mild conditions cyclometallated platinum(II) compounds [PtMe{κ2-(C,N)-4-ClC6H3CH{double bond, long}NCHRCO2Me}(SMe2)] (2a-2f). These compounds gave the corresponding phosphine derivatives [PtMe{κ2-(C,N)-4-ClC6H3CH{double bond, long}NCHRCO2Me}(PPh3)] (3a-3f). The corresponding cyclometallated platinum(IV) compounds [PtMe2I{κ2-(C,N)-4-ClC6H3CH{double bond, long}NCHRCO2Me}(PPh3)] (4) arising from intermolecular oxidative addition of methyl iodide were obtained with a high degree of stereo selectivity. Analogous results were obtained for imine 2,6-Cl2C6H3CH{double bond, long}NCH(CH2C6H5)CO2Me (1g) in a process involving intramolecular oxidative addition of a C-Cl bond. The obtained compounds were fully characterized including structure determinations for compounds 3f, 4d and 4f.
