117993-64-3Relevant academic research and scientific papers
Enantioselective Synthesis of Chiral Substituted 2,4-Diketoimidazolidines and 2,5-Diketopiperazines via Asymmetric Hydrogenation
Xiao, Guiying,Xu, Shuang,Xie, Chaochao,Zi, Guofu,Ye, Weiping,Zhou, Zhangtao,Hou, Guohua,Zhang, Zhanbin
supporting information, p. 5734 - 5738 (2021/08/01)
An enantioselective hydrogenation of 5-alkylidene-2,4-diketoimidazolidines (hydantoins) and 3-alkylidene-2,5-ketopiperazines catalyzed by the Rh/f-spiroPhos complex under mild conditions has been developed, which provides an efficient approach to the highly enantioselective synthesis of chiral hydantoins and 2,5-ketopiperazine derivatives with high enantioselectivities up to 99.9% ee.
Synthesis of chiral hydantoin derivatives by homogeneous Pd-catalyzed asymmetric hydrogenation
Ma, Bao-De,Du, Sheng-Hua,Wang, Yu,Ou, Xiao-Ming,Huang, Ming-Zhi,Wang, Li-Xin,Wang, Xiao-Guang
, p. 47 - 53 (2017/01/11)
5-Aryl substituted chiral hydantoin derivatives were synthesized via asymmetric hydrogenation of prochiral exocyclic alkenes using a Pd/BINAP catalyst. Moderate to good enantioselectivity were obtained (21–90% ee). A chiral Br?nsted acid additive was foun
Microwave-assisted solvent-free regiospecific synthesis of 5-alkylidene and 5-arylidenehydantoins
Lamiri,Bougrin,Daou,Soufiaoui,Nicolas,Giralt
, p. 1575 - 1584 (2007/10/03)
Hydantoins have become a well-known class of structures that have found significant applications as agrochemicals and therapeutics. This structural motif is of interest in the synthesis of small building blocks suitable for the preparation of potentially
REACTIONS OF CHLOROSULFONYLBENZYLIDENE HYDANTOINS
Cremlyn, Richard,Jethwa, Sanjay,Joiner, Graham,White, David
, p. 99 - 110 (2007/10/02)
5-(Benzylidene- and o-chlorobenzylidene-) and cinnamylidene-hydantoins reacted with chlorosulfonic acid to give the corresponding p-sulfonyl chlorides (1, 35, 44).These were converted into 49 derivatives by reaction with amines, hydrazines and azide ion.
