1180001-17-5 Usage
General Description
D-(S,R,R,R)-benzyl nebivolol hydrochloride is a chemical compound used in the treatment of high blood pressure and heart failure. It is a beta blocker medication that works by blocking the action of certain natural substances in the body, such as adrenaline, on the heart and blood vessels. This helps to lower blood pressure, improve blood flow, and reduce the workload on the heart. The benzyl nebivolol hydrochloride form of the medication is specifically designed to be more effective and longer-lasting in the body, making it a preferred option for some patients. It is typically administered orally and is available in various strengths, with dosages tailored to individual patient needs. As with all medications, it is important to use D-(S,R,R,R)-benzyl nebivolol hydrochloride under the supervision of a healthcare professional and to follow the prescribed dosage and instructions for use.
Check Digit Verification of cas no
The CAS Registry Mumber 1180001-17-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,0,0,0 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1180001-17:
(9*1)+(8*1)+(7*8)+(6*0)+(5*0)+(4*0)+(3*1)+(2*1)+(1*7)=85
85 % 10 = 5
So 1180001-17-5 is a valid CAS Registry Number.
1180001-17-5Relevant articles and documents
Synthesis of intermediate compound and [...] (by machine translation)
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Paragraph 0283-0284, (2020/04/09)
Synthesis of intermediate compounds [a] and [...]. [Solution] a [...], asymmetric epoxidation, sulfonyl halide in the presence of base catalyst by sulfonation, alkylation of amines, such as synthesized by a series of cross-coupling reaction. [Effect] [...] important from the viewpoint of pharmacological value, high efficiency, low cost, and which meets the requirements of industrial, optical isomers may be prepared [...] and develop a method, which is very economical in social benefit. [Drawing] no (by machine translation)
A NEW METHOD FOR PRODUCING NEBIVOLOL HYDROCHLORIDE OF HIGH PURITY
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Page/Page column 21, (2015/09/22)
The invention relates to a process for producing Nebivolol hydrochloride, (formula I) comprising the steps of: provision of a protected Nebivolol hydrochloride of the general formula (II), with P being an amine protecting group, and hydrogenation of said protected Nebivolol hydrochloride yielding Nebivolol hydrochloride of the formula (I).
