1180007-75-3Relevant academic research and scientific papers
Pd(II)-catalyzed o-C-H acetoxylation of phenylalanine and ephedrine derivatives with MeCOOOtBu/Ac2O
Vickers, Chris J.,Mei, Tian-Sheng,Yu, Jin-Quan
supporting information; experimental part, p. 2511 - 2513 (2010/07/06)
Pd(II)-catalyzed ortho C-H acetoxylation of triflate protected phenethyl- and phenpropylamines has been achieved with tert-butyl peroxyacetate as the stoichiometric oxidant and either DMF or CH3CN as the promoter. The reaction was found to tolerate a large variety of functional groups and could be combined with subsequent intramolecular amination to afford functionalized indoline derivatives.
Pd(II)-catalyzed amination of C-H bonds using single-electron or two-electron oxidants
Mei, Tian-Sheng,Wang, Xisheng,Yu, Jin-Quan
supporting information; experimental part, p. 10806 - 10807 (2009/12/04)
(Chemical Equation Presented) Pd(II)-catalyzed intramolecular amination of arenes is developed using either a one- or two-electron oxidant. The reaction protocol tolerates a wide range of deactivating groups including acetyl, cyano, and nitro groups. This catalytic reaction allows expedient syntheses of broadly useful substituted indolines or indoles.
