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Tracheal cytotoxin, Bordetella pertussis is a toxic substance produced by the bacterium Bordetella pertussis, which causes whooping cough. This cytotoxin is specifically known for its ability to damage and destroy the ciliated cells lining the respiratory tract, particularly in the trachea. Its action on these cells impairs the clearance of mucus and other secretions from the airways, leading to inflammation and facilitating the spread of the bacterium, thereby causing infection. The destruction of these cells also contributes to the characteristic symptoms of whooping cough, such as severe coughing fits and respiratory distress. Understanding the role of tracheal cytotoxin in Bordetella pertussis infection is crucial for the development of effective treatments and vaccines for whooping cough.

118013-66-4

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118013-66-4 Usage

Uses

Used in Medical Research:
Tracheal cytotoxin, Bordetella pertussis is used as a subject of study in medical research for understanding the pathogenesis of whooping cough and the mechanisms by which the bacterium causes disease. This knowledge aids in the development of targeted treatments and vaccines.
Used in Pharmaceutical Development:
In the pharmaceutical industry, tracheal cytotoxin, Bordetella pertussis is used as a target for the development of drugs and vaccines aimed at preventing or treating whooping cough. By inhibiting the action of the cytotoxin or enhancing the body's immune response against it, these treatments can potentially reduce the severity and incidence of the disease.
Used in Diagnostics:
Tracheal cytotoxin, Bordetella pertussis can also be used in the development of diagnostic tools to detect the presence of the bacterium in patients, which is important for early identification and treatment of whooping cough.
Used in Public Health Education:
Understanding the role of tracheal cytotoxin in the disease process is important for public health education, where awareness about the symptoms, transmission, and prevention of whooping cough can be increased through targeted campaigns and educational materials.

Check Digit Verification of cas no

The CAS Registry Mumber 118013-66-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,0,1 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 118013-66:
(8*1)+(7*1)+(6*8)+(5*0)+(4*1)+(3*3)+(2*6)+(1*6)=94
94 % 10 = 4
So 118013-66-4 is a valid CAS Registry Number.
InChI:InChI=1/C37H59N7O20/c1-13(30(51)44-20(35(58)59)9-10-23(48)43-19(8-6-7-18(38)34(56)57)32(53)40-14(2)33(54)55)39-31(52)15(3)61-29-25(42-17(5)47)36-60-12-22(63-36)28(29)64-37-24(41-16(4)46)27(50)26(49)21(11-45)62-37/h13-15,18-22,24-29,36-37,45,49-50H,6-12,38H2,1-5H3,(H,39,52)(H,40,53)(H,41,46)(H,42,47)(H,43,48)(H,44,51)(H,54,55)(H,56,57)(H,58,59)/t13-,14+,15+,18+,19-,20+,21+,22+,24+,25+,26+,27+,28+,29+,36+,37-/m0/s1

118013-66-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,6S)-6-[[(4R)-4-[[(2S)-2-[[(2R)-2-[[(1R,2S,3R,4R,5R)-4-acetamido-2-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,8-dioxabicyclo[3.2.1]octan-3-yl]oxy]propanoyl]amino]propanoyl]amino]-4-carboxybutanoyl]amino]-2-amino-7-[[(1

1.2 Other means of identification

Product number -
Other names Tat-BP

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:118013-66-4 SDS

118013-66-4Upstream product

118013-66-4Downstream Products

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