118015-63-7Relevant academic research and scientific papers
Hypervalent λ(n)-iodane-mediated fragmentation of tertiary cyclopropanol systems II: Application to asymmetric syntheses of piperidine and indolizidine alkaloids
Kirihara, Masayuki,Nishio, Takashi,Yokoyama, Satoshi,Kakuda, Hiroko,Momose, Takefumi
, p. 2911 - 2926 (2007/10/03)
The asymmetric synthesis of (-)-pinidine and its enantiomer was accomplished by starting from norgranatanone via the asymmetric enolization, stereoselective cyclopropanation, and oxidative ring cleavage of the resulting cyclopropanol system with a hypervalent λ(n)-iodane as key steps. Formal asymmetric synthesis of (+)-indolizidine 223AB was also performed via the asymmetric enolization and oxidative ring cleavage of the resulting cyclopropanol system as key steps.
Efficient synthesis of an enantiomeric pair of pinidine: An illustration of organochemical carving on the rigid bridged system as the stereochemical tactics
Momose, Takefumi,Nishio, Takashi,Kirihara, Masayuki
, p. 4987 - 4990 (2007/10/03)
Asymmetric synthesis of (-)-pinidine and its enantiomer was accomplished by starting from norgranatanone via the asymmetric enolization, stereoselective cyclopropanation, and oxidative ring cleavage of the resulting cyclopropanol system with a hypervalent iodoid as key steps.
Asymmetric Synthesis with α,β-Bis Ketones. Enantioselective Total Synthesis of Natural (+)-Indolizidine 195B (Bicyclic Gephyrotoxin 195B) and (-)-Pinidine and Their Enantiomers from a Common Chiral Synthon
Yamazaki, Naoki,Kibayashi, Chihiro
, p. 1396 - 1408 (2007/10/02)
The first enantioselective total synthesis of naturally occurring (+)-indolizidine 195B (bicyclic gephyrotoxin 195B) and (-)-pinidine and their enantiomers has been achieved starting from 4-O-benzyl-2,3-O-bis(methoxymethyl)-L-threitol as a single and comm
