118022-29-0Relevant academic research and scientific papers
A facile synthesis of 2-hydroxy-2-aryl 1,4-benzodioxanes
Ganesh,Harish Kumar,David Krupadanam
, p. 2069 - 2078 (1999)
Condensation of catechol with 2-bromo-1-aryl-ethanones and 2-bromo-1- aryl-propanones in dry acetone-K2CO3 medium afforded 2-hydroxy-2-aryl-1,4- benzodioxanes in good yield.
EFFECT OF PROPERTIES OF THE MEDIUM AND ELECTRONIC EFFECTS OF SUBSTITUENTS ON RING-CHAIN TAUTOMERISM IN 2-ARYL-2-HYDROXY-2,3-DIHYDRO-1,4-BENZODIOXINS
Dzvinchuk, I. B.,Lozinskii, M. O.
, p. 1954 - 1961 (2007/10/02)
The constants of the ring-chain tautomeric equilibrium in 2-aryl-2-hydroxy-2,3-dihydro-1,4-benzodioxins in various solvents were measured by PMR.The experimental data treated by means of the Palm-Koppel and Yukawa-Tsuno equations, indicate that the position of the equilibrium is determined by the joint effect of such characteristics of the medium as polarity, polarizability, and particularly general basicity and also by the electron-deficiency at the carbonyl carbon atom of the noncyclic tautomer.A tendency was found for the reaction constant to decrease and the resonance stabilization of the noncyclic tautomer to increase with increase in the nucleophilic characteristics of the solvent.
