1180236-80-9Relevant academic research and scientific papers
C5-Regioselective C-H fluorination of 8-aminoquinoline amides and sulfonamides with Selectfluor under metal-free conditions
Zhang, Yingchao,Wen, Chunxia,Li, Jizhen
, p. 1912 - 1920 (2018)
A novel and efficient regioselective C-H fluorination of 8-aminoquinoline amides and sulfonamides at the C5 position was achieved. Using Selectfluor as a "F" reagent and HOAc as an additive, the reaction proceeds smoothly via a radical pathway. This metho
Regioselective remote C5 cyanoalkoxylation and cyanoalkylation of 8-aminoquinolines with azobisisobutyronitrile
Wen, Chunxia,Zhong, Ronglin,Qin, Zengxin,Zhao, Mengfei,Li, Jizhen
supporting information, p. 9529 - 9532 (2020/09/03)
The efficient regioselective C-H cyanoalkoxylation and cyanoalkylation of 8-aminoquinoline derivatives at the C5 position have been achieved under O2 and N2 atmospheres, respectively. Using 2,2′-azobisisobutyronitrile (AIBN) as a radical precursor, the pr
Iron(iii)-catalyzed chelation assisted remote C-H bond oxygenation of 8-amidoquinolines
Vinayak, Botla,Navyasree, Pilli,Chandrasekharam, Malapaka
, p. 9200 - 9208 (2017/11/14)
Iron catalyzed site selective and chelation assisted C-H functionalization in 8-amidoquinolines is achieved. The remote C5-benzoxylation with benzoyl peroxide produced a variety of potentially bioactive 8-arylcarboxamido-5-benzoyloxy quinoline derivatives. The efficiency of the reaction reflects from the wide substrate scope with electronic differentiation on carboxamide and acyl peroxide in addition to tolerance of halo-substitutions on either of the aryls. The reaction is additive, silver free and proceeds without the exclusion of air or moisture.
Palladium-catalyzed aryl C-H bonds activation/acetoxylation utilizing a bidentate system
Gou, Fa-Rong,Wang, Xiang-Chuan,Huo, Peng-Fei,Bi, Hai-Peng,Guan, Zheng-Hui,Liang, Yong-Min
supporting information; experimental part, p. 5726 - 5729 (2010/03/01)
[Chemical Equation Presented] A palladium-catalyzed aryl C-H bonds activation/acetoxylation reaction utilizing a bidentate system has been explored. This transformation has been applied to a wide array of pyridine and 8-aminoquinoline derivatives and it exhibits excellent functional group tolerance.
