118040-97-4Relevant academic research and scientific papers
Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives
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, (2008/06/13)
The invention relates to novel processes and intermediates for the preparation of 5-amino-4-hydroxyvaleric acid derivatives of the formula STR1 in which R1 represents hydrogen, optionally substituted alkyl, cycloalkyl, cycloalkyl-lower alkyl, a
A Versatile and Stereocontrolled Synthesis of Hydroxyethylene Dipeptide Isosteres
Herold, Peter,Duthaler, Rudolph,Rihs, Grety,Angst, Christof
, p. 1178 - 1185 (2007/10/02)
An asymmetric synthesis of the hydroxyethylene dipeptide isostere unit 1 is described.The synthesis provides excellent stereocontrol over all three chiral centers and is amenable to variation of substituents R1 and R2.Key intermediat
